Phospholipid spherules (liposomes) as a model for biological membranes
نویسندگان
چکیده
منابع مشابه
Phospholipid spherules (liposomes) as a model for biological membranes.
This review describes the properties of artificial spherules composed of phospholipids and various long-chain anions or cations. The lipids, which are in the liquid-crystal state, trap aqueous solutes such as cations, anions, glucose, or glycine in aqueous compartments between a series of lipid bilayers. The diffusion of these solutes from the spherules can be studied in the same way that diffu...
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Effects of a complex polyene antibiotic, filipin, and its four components were studied upon biological (erythrocyte) and artificial (liposome) membranes in order to test the “sterol receptor” hypothesis of polyene action. The hemolytic activity of filipin complex could be removed more effectively by liposomes which had cholesterol incorporated (phosphatidyl choline (7)~dicetylphosphate (2)-chol...
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A largely unsolved problem in soft materials is how surface reconstruction competes with the rate of adsorption. Here, supported phospholipid bilayers of DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) were employed as substrates for the adsorption of a weak polyelectrolyte, polymethacrylic acid, whose time-dependent ratio of charged to uncharged functional groups served to probe the local d...
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Biological membranes play an essential role in the cellular protection as well as in the control and the transport of nutrients. Many mechanisms such as molecular recognition, enzymatic catalysis, cellular adhesion and membrane fusion take place into the biological membranes. In 1972, Singer et al. provided a membrane model, called fluid mosaic model, in which each leaflet of the bilayer is for...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1968
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)43097-4